Dear Voltage-Gated Sodium Channel aficionados,
Voltage-gated sodium channels are the basis of cellular excitability. Most of us learned about their impressively rapid gating during their first physiology classes, including that its quick opening underlies the fast upstroke of the action potential, and its fast inactivation is conveyed by a “ball-and-chain” or “hinged-lid” mechanism within the channel protein.
In recent years, high-resolution CryoEM structures confirmed and challenged some of these fundamental understandings. High-power computer analyses combined with electrophysiology, biochemistry, and more systemic methods expanded our understanding of the structure-function relation of the channels, their role in physiology, and disease.
With this lecture series, we aim to bring together sodium channel researchers worldwide to share their latest findings, engage in discussions, and further our understanding of this fascinating protein family of the human body.
We are extremely grateful to all speakers of the Edition 2022-2023. This was again a huge success. For 2024, we decided to organize an on-site conference in Grindelwald, Switzerland from Jan. 31st to Feb. 2nd, 2024. More information here.
Co-organizers: Prof. Angelika Lampert & Prof. Hugues Abriel with Dr. Jannis Körner, Dr. Oksana Iamshanova, Dr. Ana Stojiljkovic, and Dr. Jean-Sébastien Rougier.